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Search Results for Research Area: "stem cells"


Faculty Search Results: Results 1 - 20 (List more/fewer results: 10 20 30 40 )
Faculty Member Brief Research Description
Carlos Andres Aguilar Our lab uses various types of in-vivo and in-vitro models in combination with genomic assays and high-throughput sequencing to study the molecular mechanisms of muscle regeneration, development and adaptation. We are particularly interested in the role of epigenetic and transcriptional regulation (chromatin, DNAme, RNA, miRNA, lncRNA) of muscle stem cells during responses to trauma, aging and exercise and use single-cell profiling, genome editing and cell-based therapeutics to understand these phenomena.   
Rick Altschuler 1) Noise Induced and Age - Related Hearing Loss: Underlying Mechanisms and Mechanism based therapeutics for prevention and treatment; 2) Molecular mechanisms in ACTIVITY DEPENDENT PLASTICITY and TINNITUS; 3) STEM CELLS to replace lost auditory nerve  
Kate F. Barald Development/regeneration of sensory cells and neurons in the inner ear, studies of neurofibromatosis 1 using embryonic stem cell models   
Sami Barmada Mechanisms of disease in amyotrophic lateral sclerosis and frontotemporal dementia.   
Scott Barolo Research Interests: Gene regulation and cell signaling in development; Structure, function, and evolution of transcriptional enhancers.   
Stephanie Bielas Discover new genes for human developmental brain disorders and modeling disease mechanisms with patient induced pluripotent stem cells and mice to understand the associated molecular pathology.  
Dean Brenner Translational pharmacology of nutritional cancer preventive interventions, pharmacokinetics, pharmacodynamics using stem cell, eicosanoid, and fatty acid endpoints in humans, rodents.  
Laura Buttitta The goal of our lab is to understand the barriers to proliferation in quiescent cells and how they are bypassed in diseases such as cancer.  
Sally A. Camper, Ph.D. bioinformatics, cancer, developmental biology, gene expression, genetics of disease, hearing research, hormone action, neuroscience, organogenesis reproductive biology, signaling, skeletal development, stem cell research  
Maria Castro Sleeping Beauty transposase-mediated mouse brain cancer models; role of DNA repair and genomic stability in tumor progression; epigenetic studies; bioinformatics.  
Mark Chiang Our lab is focused on understanding the action of transcription factor complexes at super-enhancers that drive induction and maintenance of leukemia stem cells.  
Steven Clark We study receptor-mediated signaling that controls the maintenance and differentiation of stem cells.  
Mark S. Cohen Development of novel drugs including naturally derived withanolides, novel HSP90 inhibitors and nanoparticle drug delivery systems for improved treatment of cancers, bone and wound healing, sepsis, and endocrine diseases.  
Gabriel Corfas The Corfas Laboratory is interested in understanding the roles that interactions between neurons and glia-the two fundamental cell types of the nervous system-play in nervous system development, function and maintenance and in defining the molecular signals that orchestrate these interactions. To this end, the lab employs molecular and cellular biological techniques as well as uses genetically modified mice. Using these tools and approaches, the Corfas Laboratory has contributed to the understanding of the function of several types of glia, including oligodendrocytes, Schwann cells, astrocytes, Bergmann glia and supporting cells of the inner ear, as well as the identification of key signaling pathways that mediate the interactions between these glia and their associated neurons. The lab has also found how dysfunction of neuron-glia communication contributes to disorders of the nervous system.  
Andrzej Dlugosz Embryonic signaling pathways in cancer initiation, progression, and maintenance  
Greg Dressler My lab utilizes genetic, biochemical, and cell biological approaches to understand development, cell lineage restriction, and complex patterning.   
Keith Duncan We study the early stages of sound processing to explore development, mechanisms of hearing loss, and regenerative approaches for restoring hearing.  
Doug Engel Transcriptional regulation and genetics of hematopoietic development  
Dr. Xing Fan Study signaling pathways that regulate brain development and tumor formation to develop novel therapy targeting brain cancer stem cells.  
Eric Fearon Studies of oncogene and tumor suppressor gene defects in cancer pathogenesis, particularly gastrointestinal cancers.  
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