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Search Results for Research Area: "Cancer Biology"


Faculty Search Results: Results 1 - 20 (List more/fewer results: 10 20 30 40 )
Faculty Member Brief Research Description
Chad Brenner Bioinformatics, high-throughput siRNA/drug screening and functional genomics approaches to understand cancer biology and discover novel small molecule therapeutics.  
Laura Buttitta The goal of our lab is to understand the barriers to proliferation in quiescent cells and how they are bypassed in diseases such as cancer.  
Christine Canman Cancer Pharmacology and mechanisms promoting genome stability: We are investigating how specialized DNA polymerases are regulated by the Fanconi anemia pathway and influence the therapeutic response of cells treated with ionizing radiation or DNA crosslinking agents.   
John Carethers My translational laboratory focuses on familial colorectal cancer, in particular, the consequences of defective DNA mismatch repair.  
Arul Chinnaiyan Functional genomic, proteomic and bioinformatics approaches to study cancer and understand cancer biology as well as to discover clinical biomarkers.   
Kathleen Cho Ovarian cancer, cervical cancer, cancer genetics, cancer biology, tumor classification, mouse models of cancer, non-invasive imaging of tumor progression and drug response  
Mara Duncan The molecular mechanisms of membrane traffic, and how it promotes cell survival during stresses including starvation.  
Mohammad Fallahi-Sichani Our research is at the interface of bioengineering, cancer biology and quantitative pharmacology and combines experimental methods and data-driven computational approaches with the goal of understanding oncogenic signaling and therapeutic mechanisms in human tumors.  
David Ferguson The Ferguson laboratory studies how mammalian cells maintain a stable genome. The proteins that accomplish this serve to prevent cancer and ensure proper functioning of the immune system. Currently, our main focus is a multi-protein complex called MRN, which is mutated in human cancer predisposition and immunodeficiency syndromes. For more information see the lab website at: http://www.pathology.med.umich.edu/fergusonlab/index.html  
Ajit Joglekar mechanochemical signal transduction, Biophysics of macromolecular protein complexes using in vivo high-resolution fluorescence microscopy, image analysis, and engineered assays.  
Tom Kerppola Our laboratory investigates the regulation of transcription in mammalian cells. We use a variety of imaging approaches to visualize protein interactions and modifications in living cells and animals.  
Beth Lawlor Pediatric cancer biology with a focus on Ewing sarcoma and stem cell pathway deregulation.  
Lei Lei Germ cell fate determination during mouse oocyte differentiation. Ovarian somatic cell differentiation and its role in ovarian cancer.   
Yang Liu My laboratory studies the overlapping area of immunology, cancer biology and autoimmune diseases.  
Mats Ljungman We have developed a set of nascent RNA-seq techniques that allows us to interrogate novel aspects of transcription and post-transcriptional regulation in human cells. As part of ENCODE 4 we are using these techniques to profile human normal and cancer cells.   
Pedro Lowenstein Cancer biology and therapeutics. Self‐organization of brain tumors: cellular, molecular, and computational challenges.  
Ann Miller We study the molecular mechanisms that regulate cytokinesis in epithelial cells and how this process may become mis-regulated in cancer.   
Jacques Nor Head and neck cancer stem cells; Tumor angiogenesis; Salivary gland cancer; Cancer Biology  
Gil Omenn Leader of global Human Proteome Project, identifying, mapping, and characterizing all the proteins of the human proteome. Emphasis on alternatively spliced isoforms of transcripts and proteins and their functional consequences, predicted through use of computational methods in collaboration with Professor Yuanfang Guan and Professor Yang Zhang. Application of proteomics to Cancer Biology and Biomarker discovery. Development of the tranSMART platform for sharing of methods and datasets in drug development.  
Carole Parent The Parent laboratory has a long standing interest in understanding the signal transduction mechanisms that regulate cell migration in complex environments.   
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