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Search Results for Research Area: "Adaptive immunity"

Faculty Search Results: Results 1 - 20 (List more/fewer results: 10 20 30 40 )
Faculty Member Brief Research Description
Vern Carruthers Pathogenesis of parasitic infections: Mechanisms of cell invasion, egress and survival during infection  
Wei Cheng Molecular mechanisms of immunodeficiency caused by HIV; development of innovative prophylactic or therapeutic approaches; single-molecule manipulation, single-molecule fluorescence, optical tweezers  
Kathy Collins Our goals are to better understand molecular mechanisms of viral immune evasion and to develop strategies to inhibit these processes.  
Kate Eaton Dr. Eaton's research interests are in pathogenesis of enteric bacterial diseases. Current projects involve germ free mouse models and the pathogenesis of disease due to Shiga-toxin producing E. coli. Dr. Eaton is the director of the Germ Free mouse core.  
David Ferguson The Ferguson laboratory studies how mammalian cells maintain a stable genome. The proteins that accomplish this serve to prevent cancer and ensure proper functioning of the immune system. Currently, our main focus is a multi-protein complex called MRN, which is mutated in human cancer predisposition and immunodeficiency syndromes. For more information see the lab website at:  
A. Oveta Fuller An innovative biology-based HIV/AIDS prevention intervention through faith leader networks Mechanisms of entry and membrane fusion of human viral pathogens   
Oliver He Both bioinformatics research (e.g., ontology, literature mining, Bayesian network, and vaccine informatics) and wet-lab research (host-pathogen interactions and vaccine R&D).   
Gary Huffnagle Pulmonary immunology; fungal pathogenesis and microflora-mediated modulation of immunity   
Denise Kirschner We study the host-response to pathogens using mathematical modeling focusing on immunity to, and treatment of, Mycobacterium tuberculosis.   
Harry Mobley My laboratory is interested in the molecular mechanisms of bacterial pathogenesis. We are studying virulence mechanisms of uropathogenic Escherichia coli and Proteus mirabilis that cause urinary tract infection. We are developing vaccines that will protect against these infections.  
Beth Moore My laboratory studies both pulmonary fibrosis as well as innate and adaptive host defense post bone marrow transplantation.  
Gabriel Nunez Role of Innate Immunity in Host Defense and Disease  
Mary Oriordan Our laboratory uses genetic, molecular, and cellular approaches to investigate interactions between intracellular bacterial pathogens and their mammalian host cells.   
John Osterholzer Investigating the recruitment and function of myeloid cells (monocytes, dendritic cells, and macrophages) that accumulate in the lung in response to infection and/or injury  
Jeffrey L. Platt Transplantation Immunology, stem cell-immune system interaction, genomic stability, accommodation in transplantation and host defense   
David Sherman The Sherman laboratory works at the interface of bioorganic chemistry and molecular microbiology through the investigation of secondary metabolic systems involved in natural product biosynthesis. Several projects are being pursued in the group including genomic analysis of antibiotic biosynthesis in Streptomyces spp., investigation of the molecular genetics and biochemistry of cyanobacterial secondary metabolic systems, synthetic chemistry of complex natural product substrates to investigate the specificity and mechanisms of natural product biosynthetic enzymes, and development of culture methods for isolation of novel marine bacteria rich in of bioactive metabolite production.   
Katherine Spindler Molecular biology and pathogenesis of virus-host interactions; viral encephalitis; genetic basis of host susceptibility to mouse adenovirus infection  
Joel Swanson Quantitative fluorescence microscopic methods are used to understand how macrophage cytoplasm is organized to ingest and kill microorganisms.  
Michele Swanson To understand what determines that fate of microbes that have been ingested by macrophages, we exploit a pathogen, Legionella pneumophila.  
Jason Weinberg We use mouse adenovirus type 1 to study the pathogenesis of adenovirus respiratory infection and adenovirus myocarditis.   
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