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Faculty List for Program: "Molecular and Cellular Pathology"


Faculty Search Results: Results 1 - 20 (List more/fewer results: 10 20 30 40 )
Faculty Member Brief Research Description
Mike Bachman The immune response to bacterial iron metabolism  
Jason X. Cheng MD, PhD Dr. Jason Cheng’s research is aimed at illustrating the epigenetic and genetic mechanisms that control the generation of various blood cells and the pathogenesis of blood diseases such as leukemia, myeloproliferative neoplasms and myelodysplastic syndromes (MDS).   
Stephen Chensue See URL below http://www.pathology.med.umich.edu/chensuelab/index.htm  
Arul Chinnaiyan Functional genomic, proteomic and bioinformatics approaches to study cancer and understand cancer biology as well as to discover clinical biomarkers.   
Kathleen Cho Ovarian cancer, cervical cancer, cancer genetics, cancer biology, tumor classification, mouse models of cancer, non-invasive imaging of tumor progression and drug response  
Tomasz Cierpicki Structural studies of proteins involved in leukemogenesis. Development of small molecule compounds targeting protein-protein interactions relevant to leukemogenic transformation.  
Yali Dou Epigenetic regulation of gene expression and their implications in cancer  
Greg Dressler My lab utilizes genetic, biochemical, and cell biological approaches to understand development, cell lineage restriction, and complex patterning.   
Colin Duckett Research is focused on the role of IAP proteins in cancer, with emphasis on the potential of IAP antagonists as therapeutic agents.  
Kojo Elenitoba-Johnson Hematologic malignancies.   
Eric Fearon Studies of oncogene and tumor suppressor gene defects in cancer pathogenesis, particularly gastrointestinal cancers.  
David Ferguson The Ferguson laboratory studies how mammalian cells maintain a stable genome. The proteins that accomplish this serve to prevent cancer and ensure proper functioning of the immune system. Currently, our main focus is a multi-protein complex called MRN, which is mutated in human cancer predisposition and immunodeficiency syndromes. For more information see the lab website at: http://www.pathology.med.umich.edu/fergusonlab/index.html  
"Ken" Figueroa Role of DNA methylation in transcriptional regulation during normal and malignant hematopoiesis.   
Jason Gestwicki Chemical biology; molecular chaperones; high throughput screening; drug discovery; neurodegenerative diseases; protein misfolding; protein-protein interactions  
Jolanta Grembecka Development of small molecules for targeted therapies in cancer, with a particular focus on proteins involved in leukemogenesis.  
Cory Hogaboam Our research laboratory addresses two major themes related to chronic pulmonary disease. The first theme relates to cellular and molecular immune mechanisms that regulate the pulmonary growth and persistence of fungus in a number of experimental murine models. The second theme is more translational as we explore a grouping of clinical diseases referred to as idiopathic interstitial pneumonias (IIPs).  
Evan Keller Prostate cancer metastasis; bone metastastasis, mechanisms of aging; androgen regulation  
Celina G. Kleer, M.D. My laboratory is devoted to the discovery and validation of biomarkers of breast cancer prognosis. To this end, we are studying two pathways that are important for breast cancer initiation and metastasis. These pathways are driven by EZH2 and CCN6 (WISP3). EZH2 functions as an oncogene and CCN6 as a tumor suppressor gene. We employ cellular and molecular biology, mouse models, and human breast tissues to study their contribution to breast tumorigenesis.  
Steve Kunkel Regulation of cytokine gene expression; macrophage pathobiology.   
Beth Lawlor Pediatric cancer biology with a focus on Ewing sarcoma and stem cell pathway deregulation.  
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