||Kafsack, B.F.C., Pena, J.D.O., Coppens, I., Ravindran, S., Boothroyd, J.C., and Carruthers, V.B. (2009) Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells. Science 323;530-533. [Selected for advanced release online at Science Express as the featured article] [commentary in Disease Models and Mechanisms] [Cited in “Faculty of 1000”] [Cover illustration]
Huynh, M.-H. and Carruthers, V.B. (2009) Endogenous gene tagging in a Toxoplasma strain deficient in non-homologous recombination. Euk. Cell. 8;530-539. [Cited in “Faculty of 1000’](PMC2669203)
Harper, J., Huynh, M.-H., Coppens, I., Parussini, F., Moreno, S., Carruthers, V.B. (2006) A cleavable propeptide influences Toxoplasma infection by facilitating the trafficking and secretion of the TgMIC2-M2AP invasion complex. Mol. Biol. Cell. 17;4551-4563.
Huynh, M.-H., Carruthers, V.B. (2006) Toxoplasma MIC2 is a major determinant of invasion and virulence. PLoS Pathogens Aug 18;2(8).
Zhou, X.W., Howell, S.A., Blackman, M.J., Carruthers, V.B. (2004) Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex. Mol. Cell. Proteomics, 3;565-576. [Cover Illustration] [Cited in “Faculty of 1000”].
Brydges, S.D., Carruthers, V.B. (2003) Mutation of an unusual mitochondrial targeting sequence in SODB2 produces multiple targeting fates in Toxoplasma gondii. J. Cell Sci. 116;4675-4685.
Huynh, M.-H., Rabenau, K.E., Harper, J., Beatty, W., Sibley, L.D., Carruthers, V.B. (2003) Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex EMBO J. 22;2082-2090.
Rabenau, K.E., Sohrabi, A., Tripathy, A., Reitter, C., Ajioka, J.W., Tomley, F.M., Carruthers, V.B. (2001) TgM2AP participates in Toxoplasma gondii invasion of host cells and is tightly associated with the adhesive protein TgMIC2. Mol. Microbiol. 41;537-547
Carruthers, V.B., Giddings, O.K., and Sibley, L.D. (1999) Secretion of micronemal proteins is associated with Toxoplasma invasion of host cells. Cell. Microbiol. 1;225-235
Carruthers, V.B., and Sibley, L.D. (1997) Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts. Eur. J. Cell Biol. 73; 114-123
||Parussini, F., Coppens, I., Shah, P., Diamond, S.L., and Carruthers, V.B. (2010) Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exosomal system of Toxoplasma gondii. Mol. Microbiol. (in press). [“MicroCommentary” in the same issue]
Kafsack, B.F.C. and Carruthers, V.B. (2010) Apicomplexan perforin-like proteins. Commun. Integr. Biol. (in press).
Roiko, M.S. and Carruthers, V.B. (2009) New roles for perforins and proteases in apicomplexan egress. Cell. Microbiol. 11;1444-1452 [Cover illustration]
Larson, E.T., Parussini, F., Huynh, M.-H., Giebel, J.D., Kelley, A.M., Zhang, L., Bogyo, M., Merritt, E.A., and Carruthers, V.B. (2009) Toxoplasma gondii Cathepsin L as the primary target of the invasion inhibitory compound LHVS. J. Biol. Chem. 284;26839-26850. (PMC2785372)
Laliberté, J. and Carruthers, V.B. (2008) Host cell manipulation by the human pathogen Toxoplasma gondii. Cell. Mol. Life Sci. 65:1900-1915. (PMC2662853)