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Jochen Schacht

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Primary Appointment: Otorhinolaryngology Department
PubMed Name: schacht j
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  Several major topics are the focus of our research:
1. How the ear works: Biochemical and cell biological studies of cell communication and regulatory mechanisms in the inner ear with an emphasis on second messengers, transcription factors, gene expression.
2. How drugs cause deafness: Molecular mechanisms of cell death and translational research on prevention of drug-induced hearing loss (with emphasis on aminoglycoside antibiotics: gentamicin, kanamycin, streptomycin).
3. How our ears grow old: Mechanisms of age-related hearing loss with emphasis on oxidant stress and cell death and survival pathways.