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Search Results for Research Area: "signaling pathways"


Faculty Search Results: Results 1 - 20 (List more/fewer results: 10 20 30 40 )
Faculty Member Brief Research Description
Ben Allen Cell surface regulation of Hedgehog signaling during mouse embryogenesis.  
Scott Barolo Research Interests: Gene regulation and cell signaling in development; Structure, function, and evolution of transcriptional enhancers.   
Sally A. Camper, Ph.D. bioinformatics, cancer, developmental biology, gene expression, genetics of disease, hearing research, hormone action, neuroscience, organogenesis reproductive biology, signaling, skeletal development, stem cell research  
Maria Castro Sleeping Beauty transposase-mediated mouse brain cancer models; role of DNA repair and genomic stability in tumor progression; epigenetic studies; bioinformatics.  
Cheong-Hee Chang Studies of molecular and cellular mechanisms for T cell-mediated immunity:  
Mark Chiang Our lab is focused on understanding the action of transcription factor complexes at super-enhancers that drive induction and maintenance of leukemia stem cells.  
Kathleen Cho Ovarian cancer, cervical cancer, cancer genetics, cancer biology, tumor classification, mouse models of cancer, non-invasive imaging of tumor progression and drug response  
Gabriel Corfas The Corfas Laboratory is interested in understanding the roles that interactions between neurons and glia-the two fundamental cell types of the nervous system-play in nervous system development, function and maintenance and in defining the molecular signals that orchestrate these interactions. To this end, the lab employs molecular and cellular biological techniques as well as uses genetically modified mice. Using these tools and approaches, the Corfas Laboratory has contributed to the understanding of the function of several types of glia, including oligodendrocytes, Schwann cells, astrocytes, Bergmann glia and supporting cells of the inner ear, as well as the identification of key signaling pathways that mediate the interactions between these glia and their associated neurons. The lab has also found how dysfunction of neuron-glia communication contributes to disorders of the nervous system.  
Andrzej Dlugosz Embryonic signaling pathways in cancer initiation, progression, and maintenance  
Greg Dressler My lab utilizes genetic, biochemical, and cell biological approaches to understand development, cell lineage restriction, and complex patterning.   
Mara Duncan The molecular mechanisms of membrane traffic, and how it promotes cell survival during stresses including starvation.  
Carol Elias Our studies are focused on deciphering the mechanisms by which metabolic imbalance disrupts the reproductive neuroendocrine axis.   
Dr. Xing Fan Study signaling pathways that regulate brain development and tumor formation to develop novel therapy targeting brain cancer stem cells.  
David Ferguson The Ferguson laboratory studies how mammalian cells maintain a stable genome. The proteins that accomplish this serve to prevent cancer and ensure proper functioning of the immune system. Currently, our main focus is a multi-protein complex called MRN, which is mutated in human cancer predisposition and immunodeficiency syndromes. For more information see the lab website at: http://www.pathology.med.umich.edu/fergusonlab/index.html  
Phil Gage Cell fate decisions in neural crest and mesoderm; genetic analysis of mammalian eye development; transcription factors; cell signaling pathways  
Gary Hammer The long range objective of Dr. Hammerˇ¦s laboratory is to understand the cellular and molecular mechanisms by which signaling pathways and downstream transcription factors coordinate the specification of adrenocortical cells within the adrenal gland.  
Ajit Joglekar mechanochemical signal transduction, Biophysics of macromolecular protein complexes using in vivo high-resolution fluorescence microscopy, image analysis, and engineered assays.  
Katy Keegan Mouse models of telomere dysfunction, genomic instability, and birth defects. Molecular genetics of caudal and urogenital development.   
Evan Keller Prostate cancer metastasis; bone metastastasis, mechanisms of aging; androgen regulation; single cell analysis  
Tom Kerppola Our laboratory investigates the regulation of transcription in mammalian cells. We use a variety of imaging approaches to visualize protein interactions and modifications in living cells and animals.  
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