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Search Results for Research Area: "Structural enzymology"


Faculty Search Results: Results 1 - 20 (List more/fewer results: 10 20 30 40 )
Faculty Member Brief Research Description
Philip Andrews Major areas include the molecular architecture of organelles, phosphoprotein analysis and quantitative proteomics, interaction maps, and proteome informatics.  
Ruma Banerjee Chemical biology of mammalian sulfur metabolism, intercellular redox communication in neuro-immune function, mechanism of vitamin B12 trafficking and structural enzymology of human B12, PLP and heme enzymes and characterization of patient mutants in them.  
Bob Fuller We are interested in the basic cell biology and enzymology of protein localization and processing in the eukaryotic secretory pathway.  
Gary Glick Bio-organic chemistry; drug discovery for autoimmune diseases; molecular immunology; drug-induced apoptosis.   
Ben Margolis Our laboratory studies epithelial cell polarity and cilia formation.  
Neil Marsh Enzyme mechanisms, protein engineering and antimicrobial peptide design  
Jim Morrissey Biochemistry of the human blood clotting system; structural studies of membrane lipids bound to biologically significant ligands.  
Ruthann Nichols Heart failure is a leading cause of death. We investigate a neuropeptide which slows heartbeat and its signal transduction pathway.  
Patrick O'Brien Mechanistic studies of human DNA repair and replication proteins. Structural, functional, & biophysical studies of protein-DNA interactions and dynamics.  
Bruce Palfey We investigate enzyme reaction mechanisms using biophysical and chemical techniques, with a focus on therapeutically important flavoenzymes.  
Steve Ragsdale Enzyme Mechanisms; Metals in Biology; Redox Regulation, Metabolism of CO in Microbes and Humans, Microbial generation of energy-rich gases   
Brian Ross The research focus is on development and application of molecular imaging probes for diagnosis and treatment assessment of human diseases.  
Mark Saper Functional and structural studies of 1) capsule polysaccharide export from enteropathogenic E . coli, and 2) a lipoprotein essential for peptidoglycan cross-linking and its potential for anti-microbial development.   
Audrey Seasholtz Studies in the Seasholtz laboratory examine the molecular regulation of the mammalian stress response, focusing especially on the CRH system and the corticosteroid receptors, especially as they relate to stress, depression, anxiety and addiction.   
Janet Smith Our group studies protein structure using X-ray crystallography in order to understand protein function. We use the three-dimensional structures of proteins to understand molecular mechanisms of biological processes and to develop hypotheses about function, which we test through experiments in our lab or by collaboration.  
Debra A Thompson Mechanisms of signal transduction, vitamin A metabolism, and tissue-specific gene expression relevant to the causes and treatment of retinal dystrophy.  
Ray Trievel Our laboratory is interested in elucidating the molecular mechanisms underlying chromatin modifications that regulate gene expression and other chromatin-associated functions.  
Michael Uhler We study the role of protein phosphorylation on neuronal differentiation and homeostasis at a molecular level.  
Anne Vojtek Molecular and biochemical analysis of signaling pathways that regulate cell proliferation and neural differentiation  
Zhaohui Xu We are interested in understanding the molecular mechanism underlying protein trafficking in the cell.  
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