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Search Results for Research Area: "Inflammation and immunology"


Faculty Search Results: Results 1 - 20 (List more/fewer results: 10 20 30 40 )
Faculty Member Brief Research Description
Stephen Chensue See URL below http://www.pathology.med.umich.edu/chensuelab/index.htm  
Arul Chinnaiyan Functional genomic, proteomic and bioinformatics approaches to study cancer and understand cancer biology as well as to discover clinical biomarkers.   
Kathleen Cho Ovarian cancer, cervical cancer, cancer genetics, cancer biology, tumor classification, mouse models of cancer, non-invasive imaging of tumor progression and drug response  
Yali Dou Epigenetic regulation of gene expression and their implications in cancer  
Greg Dressler My lab utilizes genetic, biochemical, and cell biological approaches to understand development, cell lineage restriction, and complex patterning.   
Marc Hershenson rhinovirus-induced exacerbations of chronic airways disease; role of early-life viral infections in the development of asthma  
Tom Kerppola Our laboratory investigates the regulation of transcription in mammalian cells. We use a variety of imaging approaches to visualize protein interactions and modifications in living cells and animals.  
Celina G. Kleer, M.D. My laboratory is devoted to the discovery and validation of biomarkers of breast cancer prognosis. To this end, we are studying two pathways that are important for breast cancer initiation and metastasis. These pathways are driven by EZH2 and CCN6 (WISP3). EZH2 functions as an oncogene and CCN6 as a tumor suppressor gene. We employ cellular and molecular biology, mouse models, and human breast tissues to study their contribution to breast tumorigenesis.  
Andy Lieberman We use mouse and cellular models to understand mechanisms of neurodegeneration in inherited neurological diseases.  
Nick Lukacs Innate cytokine responses during viral and allergen-induced pulmonary disease. T cell differentiation, activation and novel transcriptional regulation.   
Juanita L. Merchant Primary research interests include transcriptional control mechanisms regulating cell growth and differentiation and microbial-host interactions in the upper and lower GI tract. Chronic inflammation that leads to gastric or colon cancer. Recent studies on the origin of neuroendocrine tumors has identified post-translational regulation of menin via nuclear export and proteasomal degradation  
Rich Miller Cell biology and genetics of aging in mice: stress resistance, anti-aging drugs and mutations, comparative biogerontology  
Zaneta Nikolovska-Coleska Discovery, design and development of small-molecules as new molecularly targeted therapies for cancer by applying different strategies such as high throughput screening, virtual screening and structure-based design.  
Bishr Omary Our laboratory is involved in two major areas of focus. The first involves studying the regulation, function and disease association of the cytoskeletal intermediate filament proteins that are specifically expressed in digestive-type epithelia. These proteins are termed keratin polypeptides 8, 18, 19 and 20 (K8/K18/K19/K20). The second area of focus involves studying the stress-inducible protein heme oxygenase-1 (HO-1) as a potential therapeutic target in acute pancreatitis.   
Sem Phan Pulmonary fibrosis, bone marrow myeloid progenitors in lung injury/fibrosis, amphiregulin/EGFR role in fibrosis, transcriptional regulation, role and mechanism of telomerase induction, resistin-like molecule function, progenitor/stem cell derivation of myofibroblasts, myofibroblast differentiation, epithelial-mesenchymal interactions  
David. J. Pinsky The laboratory focusses on molecular processes by which vessels change their phenotype following hypoxic/ischemic insult, harnessing endogenous protective molecules/enzymes.  
Linda Samuelson Mechanisms of development and cell transformation in stomach and intestine; Notch pathway regulation of stem and progenitor cells; cell fate determination.  
Yatrik Shah Understand the mechanisms by which cellular oxygen levels regulate inflammation and cancer  
Katherine Spindler Molecular biology and pathogenesis of virus-host interactions; viral encephalitis; genetic basis of host susceptibility to mouse adenovirus infection  
Peter A. Ward In general, the main focus of our laboratory is the regulation of the inflammatory response. In addition, we also study sepsis and some of the signalling molecules involved in the inflammatory response.   
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