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Faculty Search Results: Results 1 - 15 (List more/fewer results: 10 20 30 40 )
Faculty Member Brief Research Description
Patrick O'Brien Mechanistic studies of human DNA repair and replication proteins. Structural, functional, & biophysical studies of protein-DNA interactions and dynamics.  
Mary Oriordan Our laboratory uses genetic, molecular, and cellular approaches to investigate interactions between intracellular bacterial pathogens and their mammalian host cells.   
Sue O Very early development of the mammalian nervous system, embryonic stem cells   
James Offord   
Jennifer Ogilvie Our research combines the tools of ultrafast and single molecule spectroscopy and nonlinear microscopy to explore the diverse length and time scales of biology: from single molecules to single organisms, on time scales of femtoseconds, to seconds.   
Melanie Ohi Structural and functional studies of dynamic molecular machines using single particle cryo-electron microscopy, biochemistry, and yeast genetics.  
Puck Ohi We study mechanisms that govern microtubule organization and remodeling, with a focus on cell division.  
Laura Olsen We study the biogenesis of peroxisomes, use proteomics to discover new functions, and explore the biology of this amazing organelle.   
Michal Olszewski Our group focuses on the host-pathogen interaction at the interface of the adaptive and innate immunity. We study the effects of these interactions on the development of protective responses against fungal and bacterial pathogens. Most recently we develop models in which we study interactions of fungal pathogen within the CNS with the cells of the immune system.  
Bishr Omary Our laboratory is involved in two major areas of focus. The first involves studying the regulation, function and disease association of the cytoskeletal intermediate filament proteins that are specifically expressed in digestive-type epithelia. These proteins are termed keratin polypeptides 8, 18, 19 and 20 (K8/K18/K19/K20). The second area of focus involves studying the stress-inducible protein heme oxygenase-1 (HO-1) as a potential therapeutic target in acute pancreatitis.   
Gil Omenn Leader of global Human Proteome Project, identifying, mapping, and characterizing all the proteins of the human proteome. Emphasis on alternatively spliced isoforms of transcripts and proteins and their functional consequences, predicted through use of computational methods in collaboration with Professor Yuanfang Guan and Professor Yang Zhang. Application of proteomics to Cancer Biology and Biomarker discovery. Development of the tranSMART platform for sharing of methods and datasets in drug development.  
Akira Ono We study relationships between cellular structures (e.g., membranes and cytoskeletons) and enveloped viruses.  
Yoichi Osawa Surveillance of protein clefts by chaperones as a model of protein quality control. Regulation of Nitric Oxide Synthase through Drugs and Hsp90/Hsp70-based Chaperones.  
John Osterholzer Investigating the recruitment and function of myeloid cells (monocytes, dendritic cells, and macrophages) that accumulate in the lung in response to infection and/or injury  
Chung Owyang